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  • Recombinant SARS-CoV-2 Nucleocapsid (BA.2&BA.5/Omicron) protein C-8His

    货号: abs05114
    产品说明书
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    货号-规格 货期 价格 数量
    abs05114-100ug 现货 ¥3600.00
    - +
    abs05114-1mg 现货 ¥23000.00
    - +
    大包装询价
    概述
    种属
    SARS-CoV-2
    来源
    E.coli
    分子量
    48-50kDa(Reducing)
    外观
    Lyophilized Powder
    形态
    Lyophilized from a 0.22 μm filtered solution of PBS, pH7.4.
    性能
    序列
    Met1-Ala419
    标签
    C-8His
    纯度
    >95%SDS-PAGE&RP-HPLC
    内毒素水平
    Less than 1 EU per μg by the LAL method.
    标记
    unconjugated
    溶解方法
    Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water.
    储存/保存方法
    Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
    靶标
    背景说明
    Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has continued to adapt for human infection and transmission, resulting in several variants of concern. While most mutations occur within a single lineage, a small number are shared across multiple variants. The SARS-CoV-2 nucleocapsid (N) gene is one hotspot for coding mutations. Nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
    The mutations are identified on the SARS-CoV-2 Omicron variant Pango lineage BA.4, which included P13L, del31-33, R203K, G204R, S413R.
    Accession
    P0DTC9
    SDS-PAGE: 2μg(R: reducing conditions, N: non-reducing conditions).
    RP-HPLC
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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