(2R,3S,4R,5S)-1-丁基-2-(羟基甲基)-3,4,5-哌啶三醇

N-(n-Butyl)deoxygalactonojirimycin is an extremely potent and selective α-gal A (a-D-galactosidase) inhibitor. Also a selective inhibitior of GlcCer synthesis.

A potent and selective inhibitor of α-D-galactosidase

98%

Store at -20° C

Solid

3,4,5-Piperidinetriol,1-butyl-2-(hydroxymethyl)-, [2R-(2a,3a,4a,5b)]-; N-Butyldeoxygalactonojirimycin

~1.2 g/cm³ (Predicted)

123-124° C

~394.7° C at 760 mmHg (Predicted)

n²⁰_D 1.55 (Predicted)

β-glucosidase: IC₅₀ = 0.3 µM (human); Sucrase-Isomaltase: IC₅₀ = 0.46 µM (human); LYAG: IC₅₀ = 1.5 µM (human); Maltase-glucoamylase: IC₅₀ = 10 µM (human); AGL: IC₅₀ = 10 µM (human)

pK_a: 13.72 (Predicted), pK_b: 6.94 (Predicted)

Soluble in methanol (5 mg/ml), and water (1 mg/ml).

MFCD00269939

501391