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  • Recombinant Mouse Myostatin/MSTN/GDF-8 (C-6His)
  • Growth/differentiation factor 8,GDF-8,Myostatin,Mstn,Gdf8
  • 货号: abs04360
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs04360-10ug 1-2周 ¥1260.00
    - +
    abs04360-50ug 1-2周 ¥3696.00
    - +
    abs04360-500ug 1-2周 ¥12936.00
    - +
    abs04360-1mg 1-2周 ¥19200.00
    - +
    大包装询价
    概述
    描述
    Recombinant Mouse Growth Differentiation Factor 8 is produced by our Mammalian expression system and the target gene encoding Asn25-Ser265 is expressed with a 6His tag at the C-terminus.
    别名
    Growth/differentiation factor 8,GDF-8,Myostatin,Mstn,Gdf8
    来源
    Human Cells
    形态
    Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
    性能
    氨基酸序列
    NEGSEREENVEKEGLCNACAWRQNTRYSRIEAIKIQILSKLRLETAPNISKDAIRQLLPRAPPLR ELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQADGKPKCCFFKFSSKIQYNKVVK AQLWIYLRPVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMSPGTGIWQSIDVKTVLQNWLKQ PESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSVDHHHHHH
    纯度
    Greater than 95% as determined by reducing SDS-PAGE.
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    溶解方法
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    靶标
    背景说明
    Mouse Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues. Experiments in mice have improved that GDF-8 is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking Myostatin encoding gene show decreased body fat and a generalized increase in bone density and strength.
    Accession
    O08689
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