MG149
- MG 149；MG-149；Tip60 HAT inhibitor
货号： abs811514
| 货号-规格 | 货期 | 价格 | 数量 |
| abs811514-5mg | 4周 | ￥1313.00 | - + |
| abs811514-10mg | 4周 | ￥2345.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF. | |
| 纯度 | >98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | MG 149；MG-149；Tip60 HAT inhibitor | |
| 可溶性/溶解性 | DMSO : ≥ 100 mg/mL (293.72 mM) | |
| 生物活性 | ||
| 靶点 | Histone Acetyltransferase | |
| In vitro(体外研究) | MG 149 (Tip60 HAT inhibitor), at 200 μM, inhibited about 90% of Tip60 activity but had no inhibitory impact on p300 and PCAF. MG 149 was essentially competitive with Ac-CoA and noncompetitive with the histone substrate. HAT inhibition studies with MG 149 demonstrated that both compounds inhibited the HAT activity of the nuclear extracts of different regions significantly (p < 0.05). | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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Certificate of Analysis(COA)
