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  • LTURM34
  • LTURM 34;LTURM-34
  • 货号: abs814482
    CAS号: 1879887-96-3
    分子式: C24H18N2O3S
    分子量: 414.48
    产品说明书
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    货号-规格 货期 价格 数量
    abs814482-5mg 1-2周 ¥1103.00
    - +
    abs814482-25mg 1-2周 ¥3780.00
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    大包装询价
    产品描述
    描述

    LTURM34 is a specific DNA-PK inhibitor with an IC50 of 0.034 uM. LTURM34 shows potent inhibition of DNA-PK with excellent selectivity over the Class I PI3K isoforms. The IC50s are 5.8 and 8.5 uM for PI3K β and δ, respectively. LTURM34 shows potent and broad ranging antiproliferative activity. LTURM34 is more consistently active against the selected cell lines (11 of 16), but at best shows 54% inhibition against the HOP-92 non-small cell lung cancer line.

    纯度
    >98%
    储存/保存方法
    Store at -20°C
    基本信息
    别名
    LTURM 34;LTURM-34
    外观
    Powder
    可溶性/溶解性
    DMSO : ≥ 37.5 mg/mL (90.47 mM)
    生物活性
    靶点
    DNA-PK
    In vitro(体外研究)
    LTURM34 shows potent inhibition of DNA-PK with excellent selectivity over the Class I PI3K isoforms. The IC50s are 5.8 and 8.5 μM for PI3K β and δ, respectively. LTURM34 shows potent and broad ranging antiproliferative activity. LTURM34 is more consistently active against the selected cell lines (11 of 16), but at best shows 54% inhibition against the HOP-92 non-small cell lung cancer line.
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