(R)-(+)-α-Lipoic acid
- (R)-(+)-α-硫辛酸；(+)-α-Lipoic acid；α-Lipoic acid
货号： abs814915
| 货号-规格 | 货期 | 价格 | 数量 |
| abs814915-500mg | 1-2周 | ￥607.00 | - + |
| abs814915-1g | 1-2周 | ￥938.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | R(+)-α-lipoic acid, a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. | |
| 纯度 | ＞98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 形态 | Solid | |
| 基本信息 | ||
| 别名 | (R)-(+)-α-硫辛酸；(+)-α-Lipoic acid；α-Lipoic acid | |
| 外观 | yellow crystalline | |
| 可溶性/溶解性 | DMSO ：41 mg/mL (198.71 mM) | |
| 生物活性 | ||
| In vitro(体外研究) | Using L6 myotubes and 3T3-L1 adipocytes as a model of muscle and fat cells in culture, R(+)-α-lipoic acid (R-LA) is shown to increase tyrosine phosphorylation of insulin receptor and IRS-1, to enhance PI 3-kinase and Akt1 activities, to elevate GLUT4 content in the plasma membranes, and to increase glucose uptake into the cells. 3T3-L1 adipocytes possess a low capacity to reduce R-α-lipoic acid and the oxidized isoforms are effective in stimulating glucose transport. R-α-lipoic acid modulates glucose transport by changing intracellular redox status. Insulin receptor is a target of R-LA action. | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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