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  • Recombinant Mouse Interleukin-23/IL-23
  • SGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2
  • 货号: abs04583
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs04583-10ug 1-2周 ¥1512.00
    - +
    abs04583-50ug 1-2周 ¥4536.00
    - +
    abs04583-500ug 1-2周 ¥20580.00
    - +
    abs04583-1mg 1-2周 ¥28000.00
    - +
    大包装询价
    概述
    描述

    Recombinant Mouse Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Val22-Ala196&Met23-Ser335 is expressed.

    别名
    SGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2
    来源
    Human Cells
    形态
    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    性能
    氨基酸序列
    VPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDN SQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSL SSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA&MWELEKDVYVVEVDWTPDA PGETVNLTCDTPEEDDITWTSDQRHGVIGSGKTLTITVKEFLDAGQYTCHKGGETLSHSHLLLHK KENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFNIKSSSSSPDSRAVTCGMAS LSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEARQQNKYENYSTSFFIRDIIKPDPP KNLQMKPLKNSQVEVSWEYPDSWSTPHSYFSLKFFVRIQRKKEKMKETEEGCNQKGAFLVEKTST EVQCKGGNVCVQAQDRYYNSSCSKWACVPCRVRS
    纯度
    Greater than 95% as determined by reducing SDS-PAGE.
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    溶解方法
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    储存/保存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    靶标
    背景说明
    Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
    Accession
    Q9EQ14&P43432
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