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  • Recombinant Mouse Interleukin-16/IL-16
  • Pro-interleukin-16,Interleukin-16,Lymphocyte chemoattractant factor,LCF, REF: C1011
  • 货号: abs04469
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs04469-10ug 1-2周 ¥882.00
    - +
    abs04469-50ug 1-2周 ¥2646.00
    - +
    abs04469-500ug 1-2周 ¥12936.00
    - +
    abs04469-1mg 1-2周 ¥17600.00
    - +
    大包装询价
    概述
    描述
    Recombinant Mouse Interleukin-16 is produced by our E.coli expression system and the target gene encoding Ser1205-Ser1322 is expressed with a 6His tag at the N-terminus.
    别名
    Pro-interleukin-16,Interleukin-16,Lymphocyte chemoattractant factor,LCF, REF: C1011
    来源
    Escherichia coli.
    形态
    Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH 8.0.
    性能
    氨基酸序列
    MGSSHHHHHHSSGLVPRGSHMSAASASAASDISVESKEATVCTVTLEKTSAGLGFSLEGGKGSLH GDKPLTINRIFKGTEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQC KQTTASADS
    纯度
    Greater than 95% as determined by reducing SDS-PAGE.
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    溶解方法
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    靶标
    背景说明
    Mouse interleukin-16(IL-16) is a single chain non-glycosylated polypeptide. IL-16 is widely expressed in human tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. IL-16 plays an important role instimulating a migratory response in CD4+ lymphocytes, monocytes, and eosinophils,inducing T-lymphocyte expression of interleukin 2 receptor.It was originally identified as a CD8+ T cell-derived chemoattractant for CD4+ cells. In addition to its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro and appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. It may act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
    Accession
    O54824
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