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  • Recombinant Mouse Insulin-like Growth Factor I/ LR3-IGF1 (C-6His)
  • IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C
  • 货号: abs04634
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs04634-10ug 1-2周 ¥252.00
    - +
    abs04634-50ug 1-2周 ¥420.00
    - +
    abs04634-500ug 1-2周 ¥4200.00
    - +
    abs04634-1mg 1-2周 ¥5600.00
    - +
    大包装询价
    概述
    描述

    Recombinant Mouse Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed with a 6His tag at the C-terminus.

    别名
    IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C
    来源
    Escherichia coli.
    形态
    Lyophilized from a 0.2 μm filtered solution of 20mM NaAc, pH 4.5.
    性能
    氨基酸序列
    MFPAMPLSSLFVNGGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQTGIVDECCFRS CDLRRLEMYCAPLKPTKAALEHHHHHH
    纯度
    Greater than 95% as determined by reducing SDS-PAGE.
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    溶解方法
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    储存/保存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    靶标
    背景说明
    Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
    Accession
    P05017
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