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  • GNF351

    货号: abs820388
    CAS号: 1227634-69-6
    分子式: C24H25N7
    分子量: 411.50
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    货号-规格 货期 价格 数量
    abs820388-5mg 4周 ¥1455.00
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    abs820388-25mg 4周 ¥5027.00
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    大包装询价
    产品描述
    描述
    GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes.
    纯度
    98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    生物活性
    In vitro(体外研究)
    GNF351 (500 nM, 48 hours) significantly reduces the percentage of Ki67-positive cells and cell number after treating proliferating monolayer cultures of human keratinocytes.Cell Proliferation AssayCell Line:Human primary keratinocytesConcentration:500 nMIncubation Time:48 hoursResult:Showed a significant reduction in the percentage of Ki67-positive cells and cell number after treating proliferating monolayer cultures of human keratinocytes for 48 hours.
    In vivo(体内研究)
    GNF351 (500 nM, 48 hours) significantly reduces the percentage of Ki67-positive cells and cell number after treating proliferating monolayer cultures of human keratinocytes.Cell Proliferation AssayCell Line:Human primary keratinocytesConcentration:500 nMIncubation Time:48 hoursResult:Showed a significant reduction in the percentage of Ki67-positive cells and cell number after treating proliferating monolayer cultures of human keratinocytes for 48 hours.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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