货号： abs821664
| 货号-规格 | 货期 | 价格 | 数量 |
| abs821664-5mg | 4周 | ￥3308.00 | - + |
| abs821664-25mg | 4周 | ￥11907.00 | - + |
大包装询价| 产品描述 | |
| 描述 | GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. |
| 纯度 | 98% |
| 储存/保存方法 | store at -20℃ for one year（Powder） |
| 生物活性 | |
| In vitro(体外研究) | GCN2iB shows an IC50 value of 2.4 nM for GCN2 and potent cellular activity. In a panel of 468 kinases, only GCN2 shows >99.5% inhibition, and three kinases (MAP2K5, STK10, and ZAK) show >95%inhibition at 1 μM GCN2iB, demonstrating high kinase selectivity. |
| In vivo(体内研究) | GCN2iB shows an IC50 value of 2.4 nM for GCN2 and potent cellular activity. In a panel of 468 kinases, only GCN2 shows >99.5% inhibition, and three kinases (MAP2K5, STK10, and ZAK) show >95%inhibition at 1 μM GCN2iB, demonstrating high kinase selectivity. |
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Certificate of Analysis(COA)
