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  • Ethidium bromide
    • EtBr; Dromilac; 3,8-Diamino-5-ethyl-6-phenylphenanthridinium bromide
    货号: abs42017967
    CAS号: 1239-45-8
    分子式: C21H20N3 Br
    分子量: 394.3
    产品说明书
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    货号-规格 货期 价格 数量
    abs42017967-1g 1-2周 ¥560.00
    - +
    abs42017967-5g 1-2周 ¥1897.00
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    大包装询价
    产品描述
    描述

    Ethidium bromide is a polyaromatic fluorescent small molecule and nucleic acid intercalator widely used as a stain in DNA and RNA electrophoresis. Upon intercalation into the hydrophobic region between nucleic acid base pairs, fluorescence-quenching water molecules associated to the Ethidium bromide structure are displaced and the bound Ethidium bromide then fluoresces very strongly compared to free Ethidium bromide (~25 fold increase in dsDNA). Intercalation distorts the ribonucleic acid structure and impedes natural DNA interactions, presenting a powerful mutagen effect associated with Ethidium bromide. This imposition on DNA structure also makes Ethidium bromide an inhibitor of DNA polymerase.

    应用
    An intercalating fluorescent dye reagent for DNA/RNA staining
    纯度
    95%
    储存/保存方法
    Store at RT
    基本信息
    别名
    EtBr; Dromilac; 3,8-Diamino-5-ethyl-6-phenylphenanthridinium bromide
    外观
    red to purple powder
    可溶性/溶解性
    water (10 mg/mL)
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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