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  • Estrone-d2
    • E1-d2;
    货号: abs47045749
    CAS号: 350820-16-5
    分子式: C18H20D2O2
    分子量: 272.4
    产品说明书
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    货号-规格 货期 价格 数量
    abs47045749-1mg 4周 ¥1779.00
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    大包装询价
    产品描述
    描述
    Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165 | 10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155 | 10006315) and estriol (Item Nos. ISO60164 | 10006484).1 Estrone is synthesized from androstenedione (Item No. ISO60161) by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.1,2 Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.1 The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.1
    纯度
    ≥98%
    储存/保存方法
    Store at -20℃
    基本信息
    别名
    E1-d2;
    参考文献
    参考文献
    1.Gruber, C.J.,Tschugguel, W.,Schneeberger, C., et al. Production and actions of estrogens. New England Journal of Medicine 346(5), 340-352 (2002).

    2.Vance, D.E. Cholesterol and related derivatives. Biochemistry 2nd ed., 725-748 (1988).

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