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  • Recombinant Human Estrogen Receptor α/ERα/NR3A1 (N-6His)
    • Estrogen Receptor, ER, ER-Alpha, Estradiol Receptor, Nuclear Receptor Subfamily 3 Group A Member 1, ESR1, ESR, NR3A1
    货号: abs04404
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs04404-10ug 1-2周 ¥1323.00
    - +
    abs04404-50ug 1-2周 ¥3881.00
    - +
    abs04404-500ug 1-2周 ¥13583.00
    - +
    abs04404-1mg 1-2周 ¥18480.00
    - +
    大包装询价
    概述
    描述
    Recombinant Human Estrogen receptor alpha is produced by our E.coli expression system and the target gene encoding Met1-Gln116 is expressed with a 6His tag at the N-terminus.
    中文别名
    Estrogen Receptor, ER, ER-Alpha, Estradiol Receptor, Nuclear Receptor Subfamily 3 Group A Member 1, ESR1, ESR, NR3A1
    来源
    Escherichia coli.
    形态
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
    性能
    氨基酸序列
    MGSSHHHHHHSSGLVPRGSHMTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLD SSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLML LHPPPQ
    纯度
    Greater than 95% as determined by reducing SDS-PAGE.
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    溶解方法
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    靶标
    背景说明
    Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
    Accession
    P03372
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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