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  • Estriol-d2
    • E3-d2;16α-hydroxy-17β-Estradiol-d2;1,3,5(10)-Estratriene-3,16α,17β-triol-d2;
    货号: abs47045890
    CAS号: 53866-32-3
    分子式: C18H22D2O3
    分子量: 290.4
    产品说明书
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    货号-规格 货期 价格 数量
    abs47045890-1mg 4周 ¥6145.00
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    产品描述
    描述
    Estriol-d2 is intended for use as an internal standard for the quantification of estriol (Item Nos. ISO60164 | 10006484) by GC- or LC-MS. Estriol is a metabolite of estradiol (Item Nos. ISO60155 | 10006315) and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from <10 ng/ml at 8-10 weeks gestation to approximately 150 ng/ml at week 38.1 The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS; Item No. 15873) and serves as a direct marker of fetal adrenal gland activity.2 Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels.2,3 Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.4
    纯度
    ≥98%
    储存/保存方法
    Store at -20℃
    基本信息
    别名
    E3-d2;16α-hydroxy-17β-Estradiol-d2;1,3,5(10)-Estratriene-3,16α,17β-triol-d2;
    参考文献
    参考文献
    1.Peter, M.,Dörr, H.G. and Sippell, W.G. Changes in the concentrations of dehydroepiandrosterone sulfate and estriol in maternal plasma during pregnancy: A longitudinal study in healthy women throughout gestation and at term. Hormone Research 42, 278-281 (1994).

    2.Goodwin, T.M. A role for estriol in human labor, term and preterm. American Journal of Obstetics and Gynecology 180, S208-S213 (1999).

    3.Voss, H.F. Hormonal pathways of preterm birth. American Journal of Obstetics and Gynecology 180, S226-S231 (1999).

    4.. Steroid levels in humans. (1999).

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