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  • Esomeprazole Sodium
    • 埃索美拉唑钠;(S)-Omeprazole sodium
    货号: abs816319
    CAS号: 161796-78-7
    分子式: C17H18N3O3S.Na
    分子量: 367.4
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs816319-2mg 1-2周 ¥1031.00
    - +
    abs816319-5mg 1-2周 ¥1339.00
    - +
    abs816319-10mg 1-2周 ¥2503.00
    - +
    abs816319-25mg 1-2周 ¥4269.00
    - +
    大包装询价
    产品描述
    描述

    Esomeprazole sodium (Nexium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg. Esomeprazole sodium (Nexium) suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. Esomeprazole sodium (Nexium) is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease and Zollinger-Ellison syndrome. Esomeprazole is the S-enantiomer of omeprazole. The S- and R-isomers of omeprazole are protonated and converted in the acidic compartment of the parietal cell forming the active inhibitor, the achiral sulphenamide. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity. This effect is dose-related up to a daily dose of 20 to 40 mg and leads to inhibition of gastric acid secretion.

    纯度
    >98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    中文别名
    埃索美拉唑钠;(S)-Omeprazole sodium
    外观
    白色至浅黄色粉末
    可溶性/溶解性
    Ethanol :68 mg/mL (185.1 mM)

    DMSO :68 mg/mL (185.1 mM)

    Water :67 mg/mL (182.4 mM)
    生物活性
    靶点
    Proton Pump
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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