首页 产品中心
  • Esmolol hydrochloride
    • 盐酸艾司洛尔
    货号: abs813630
    CAS号: 81161-17-3
    分子式: C16H25NO4.HCl
    分子量: 331.83
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs813630-25mg 1-2周 ¥497.00
    - +
    abs813630-50mg 1-2周 ¥827.00
    - +
    abs813630-100mg 1-2周 ¥1158.00
    - +
    大包装询价
    产品描述
    描述

    Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.

    纯度
    >98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    中文别名
    盐酸艾司洛尔
    外观
    白色或类白色结晶性粉末
    可溶性/溶解性
    Ethanol :61 mg/mL (184.2 mM)

    DMSO :61 mg/mL (184.2 mM)

    Water :61 mg/mL (184.2 mM)
    生物活性
    靶点
    beta-adrenergic receptor
    In vitro(体外研究)
    Esmolol contains one asymmetric centre and exists as an enantiomeric pair, the (-)-enantiomer is active and the (+)-enantiomer is inactive, which is analogous to other P-blockers that have an oxypropranolamine nucleus. Esmolol has a rapid onset and offset of activity, the primary site of activity of Esmolol is on sinus node and atrioventricular (AV) nodal conduction systems.
    In vivo(体内研究)
    Esmolol (20 mg/kg) infusion in sepsis improves oxygen utilization of myocardium and preserves myocardial function in septic rats. Esmolol (5 mg/kg, i.v.) produces a dose-dependent decrease in heart rate (HR) in rabbits, with the maximum percent reductions of 13%. Esmolol (5 mg/kg, i.v.) produces a dose-dependent decrease in mean arterial pressure (MAP) in rabbits, with the maximum percent reductions of 38.2%. Esmolol (300 mg/kg) significantly decreases the heart rate, rate-pressure product, left ventricular contraction, cardiac output, and relative refractory period of the right ventricle, suppresses the AV nodal conduction, and increases the effective refractory period of the right ventricle and the preload of the left ventricle in canine. Esmolol (300 mg/kg) significantly reduces the isoproterenol-induced increase in heart rate and ventricular contraction in canine.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
      0张,还能上传 8 提交
          提示: 尊敬的客户您好,如果您对我们的产品有什么疑问或想要了解的,可以点击“我要提问”按钮填写您的疑问。
          提交不成功?请联系info@absin.cn。
          我要提问

      促销资讯 更多

        订购信息
        您可以从我们的授权经销商处购买absin产品或获得技术支持。若要查看您所在地区的经销商,请从以下的下拉列表中选择。
        GO
        • 0