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  • Dehydroevodiamine hydrochloride
    • 盐酸去氢吴茱萸碱
    货号: abs814675
    CAS号: 111664-82-5
    分子式:  C19H15N3O.HCl
    分子量: 337.8
    产品说明书
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    货号-规格 货期 价格 数量
    abs814675-25mg 4周 ¥1682.00
    - +
    abs814675-100mg 4周 ¥4632.00
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    大包装询价
    产品描述
    描述

    Dehydroevodiamine (DHE), a major phytochemical in fruits of Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.

    纯度
    ≥98%
    储存/保存方法
    Store at -20°C
    基本信息
    别名
    盐酸去氢吴茱萸碱
    外观
    Yellow powder
    可溶性/溶解性
    DMSO :37 mg/mL (109.53 mM)
    生物活性
    靶点
    AChE
    In vitro(体外研究)
    Dehydroevodiamine·HCl (DHED) treatment significantly recovers the decreases in the levels of neural cell adhesion molecule (NCAM) proteins caused by stress and the decreases in cell viability. It decreases intracellular calcium levels in primary cortical neurons.
    In vivo(体内研究)
    Dehydroevodiamine·HCl (DHED) can improve stress-induced memory impairments and depression-like behaviors. DHED significantly improves learning and memory in the Aβ1-42-infused rat model. Antiamnestic effects of DHED occur through an improvement of learning and memory and an inhibition of neuronal dysfunction in a scopolamine-induced amnesic rat model. Furthermore, Dehydroevodiamine·HCl (DHED) has hypotensive and neuroprotective effects and modulates nitric oxide production.
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