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  • CK7 antibody
  • CK 7; CK-7; CK7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 7; Keratin 7, type II; Keratin type II cytoskeletal 7; Keratin, 55K type II cytoskeletal; Keratin, simple epithelial; Keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Krt2-7; KRT7; MGC11625; MGC129731; MGC3625; Sarcolectin; SCL; Type II mesothelial keratin K7; Type-II keratin Kb7;
  • 货号: abs132254
    产品说明书
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    货号-规格 货期 价格 数量
    abs132254-50ug 现货 ¥1100.00
    - +
    abs132254-100ug 1-2周 ¥1650.00
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    大包装询价
    概述
    描述
    CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
    别名
    CK 7; CK-7; CK7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 7; Keratin 7, type II; Keratin type II cytoskeletal 7; Keratin, 55K type II cytoskeletal; Keratin, simple epithelial; Keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Krt2-7; KRT7; MGC11625; MGC129731; MGC3625; Sarcolectin; SCL; Type II mesothelial keratin K7; Type-II keratin Kb7;
    宿主
    Mouse
    特异性
    CK7 antibody detects endogenous levels of total CK7
    反应种属
    Human
    应用
    ELISA 1/10000, WB 1/500 - 1/2000, FCM 1/200 - 1/400, ELISA(peptide) 1:20000-1:40000
    免疫原
    Purified recombinant fragment of human CK7 expressed in E. Coli
    性能
    浓度
    1mg/ml
    纯化方法
    Affinity-chromatography
    类型
    Monoclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
    靶标
    背景说明
    Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
    组织特异性
    Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
    翻译后修饰
    Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
    细胞定位
    Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;
    UniPort
    Figure 1: Western blot analysis using CK7 mouse mAb against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate.
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