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  • CGP-53153
  • 货号: abs820867
    CAS号: 149281-19-6
    分子式: C23H33N3O2
    分子量: 383.53
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs820867-1mg 4周 ¥2520.00
    - +
    abs820867-5mg 4周 ¥5040.00
    - +
    大包装询价
    产品描述
    描述
    CGP-53153 is a steroidal inhibitor of 5 alpha reductase with IC50s of 36 and 262 nM in rat and human prostatic tissue, respectively.
    储存/保存方法
    store at -20℃ for one year(Powder)
    基本信息
    可溶性/溶解性
    DMSO*
    生物活性
    In vitro(体外研究)
    CGP-53153 competitively inhibits rat microsomal 5 alpha reductase from prostate with an IC50 of 36 nM compared to the reference compound finasteride (IC50=11 nM). CGP 53153 is approximately one order of magnitude more potent in inhibiting rat compared to human 5 alpha reductase, with IC50 values of 36 and 262 nM, respectively
    In vivo(体内研究)
    CGP-53153 competitively inhibits rat microsomal 5 alpha reductase from prostate with an IC50 of 36 nM compared to the reference compound finasteride (IC50=11 nM). CGP 53153 is approximately one order of magnitude more potent in inhibiting rat compared to human 5 alpha reductase, with IC50 values of 36 and 262 nM, respectively
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