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  • Cangrelor Tetrasodium

    • 坎格雷洛四钠盐;AR-C69931MX;AR-C69931
    货号: abs814683
    CAS号: 163706-36-3
    分子式:  C17H21Cl2F3N5Na4O12P3S2
    分子量: 864.29
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs814683-5mg 1-2周 ¥992.00
    - +
    abs814683-25mg 1-2周 ¥3087.00
    - +
    大包装询价
    产品描述
    描述

    Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.

    纯度
    98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    别名
    坎格雷洛四钠盐;AR-C69931MX;AR-C69931
    外观
    powder
    可溶性/溶解性
    DMSO :2 mg/mL (2.31 mM)

    Water :100 mg/mL (115.70 mM)
    生物活性
    靶点
    P2Y12 receptor
    In vitro(体外研究)
    Cangrelor is an intravenous ATP analog that directly inhibits, without the need for being metabolized, the P2Y12 receptor in a reversible manner. Cangrelor has a rapid-onset and -offset mechanism of action and achieves significantly greater degrees of platelet inhibition compared with clopidogrel.
    In vivo(体内研究)
    Cangrelor is rapidly deactivated by plasmatic ectonucleotidases and, thus, has an extrmely short half-life (2-5 min). Preclinical studies performed in animal models in the early stages of cangrelor development show efficacy in inhibiting thrombus formation and ADP-induced platelet aggregation, as well as a lower increase of bleeding times when compared with IIb/IIIa antagonist.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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