Cangrelor Tetrasodium
- 坎格雷洛四钠盐；AR-C69931MX；AR-C69931
货号： abs814683
| 货号-规格 | 货期 | 价格 | 数量 |
| abs814683-5mg | 1-2周 | ￥992.00 | - + |
| abs814683-25mg | 1-2周 | ￥3087.00 | - + |
大包装询价| 产品描述 | |
| 描述 | Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation. |
| 纯度 | 98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 坎格雷洛四钠盐；AR-C69931MX；AR-C69931 |
| 外观 | powder |
| 可溶性/溶解性 | DMSO ：2 mg/mL (2.31 mM) Water ：100 mg/mL (115.70 mM) |
| 生物活性 | |
| 靶点 | P2Y12 receptor |
| In vitro(体外研究) | Cangrelor is an intravenous ATP analog that directly inhibits, without the need for being metabolized, the P2Y12 receptor in a reversible manner. Cangrelor has a rapid-onset and -offset mechanism of action and achieves significantly greater degrees of platelet inhibition compared with clopidogrel. |
| In vivo(体内研究) | Cangrelor is rapidly deactivated by plasmatic ectonucleotidases and, thus, has an extrmely short half-life (2-5 min). Preclinical studies performed in animal models in the early stages of cangrelor development show efficacy in inhibiting thrombus formation and ADP-induced platelet aggregation, as well as a lower increase of bleeding times when compared with IIb/IIIa antagonist. |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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Certificate of Analysis(COA)
