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  • Buclizine hydrochloride
    • 盐酸安其敏
    货号: abs813532
    CAS号: 129-74-8
    分子式: C28H33ClN2.2HCl
    分子量: 505.95
    产品说明书
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    货号-规格 货期 价格 数量
    abs813532-100mg 1-2周 ¥473.00
    - +
    abs813532-500mg 1-2周 ¥1418.00
    - +
    大包装询价
    产品描述
    描述

    Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family.

    纯度
    >98%
    储存/保存方法
    store at -20℃ for one year(Powder);
    in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
    基本信息
    别名
    盐酸安其敏
    外观
    白色粉末
    可溶性/溶解性
    DMSO : 2.5 mg/mL (4.94 mM; Need ultrasonic)
    生物活性
    靶点
    Histamine receptor;Cholinergic
    In vitro(体外研究)
    Buclizine hydrochloride, a piperazine derivative, is a sedating antihistamine with antimuscarinic and moderate sedative action. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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