首页 产品中心
  • BLU-554

    • BLU-554
    货号: abs818293
    CAS号: 1707289-21-1
    分子式: C24H24Cl2N4O4
    分子量: 503.38
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs818293-1mg 1-2周 ¥650.00
    - +
    abs818293-5mg 1-2周 ¥1350.00
    - +
    abs818293-10mg 1-2周 ¥2150.00
    - +
    abs818293-50mg 1-2周 ¥6150.00
    - +
    大包装询价
    产品描述
    描述
    Fisogatinib (BLU-554) is a potent fibroblast growth factor receptor 4 (FGFR4) inhibitor.
    纯度
    98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    别名
    BLU-554
    可溶性/溶解性
    DMSO : 100 mg/mL (198.66 mM; Need ultrasonic)
    生物活性
    靶点
    FGFR
    In vitro(体外研究)
    Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR-4 gene. This protein is a member of the fibroblast growth factor receptor family, where amino acid sequence was highly conserved between members throughout evolution. FGFR family members 1-4 differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of the FGFR-4 gene encompasses 18 exons. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the Iglll domain of this protein varies between three alternate forms, as indicated for FGFR 1-3.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
      0张,还能上传 8 提交
          提示: 尊敬的客户您好,如果您对我们的产品有什么疑问或想要了解的,可以点击“我要提问”按钮填写您的疑问。
          提交不成功?请联系info@absin.cn。
          我要提问

      促销资讯 更多

        订购信息
        您可以从我们的授权经销商处购买absin产品或获得技术支持。若要查看您所在地区的经销商,请从以下的下拉列表中选择。
        GO
        • 0