BIX-01294
促销商品- BIX 01294; BIX01294,BIX-01294
货号: abs810698
货号-规格 | 货期 | 价格 | 数量 |
abs810698-5mg | 现货 | - + | |
abs810698-50mg | 现货 | - + |

产品描述 | ||
描述 | BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM. | |
纯度 | >98% | |
储存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. | |
基本信息 | ||
别名 | BIX 01294; BIX01294,BIX-01294 | |
外观 | Off-white solid | |
可溶性/溶解性 | H2O : 14.29 mg/mL (29.13 mM; Need ultrasonic) | |
生物活性 | ||
靶点 | G9a | |
In vitro(体外研究) | BIX-01294 (4.1 μM) treatment of G9anull ES cells results in a further reduction in H3K9me2 levels. BIX-01294 reduces H3K9me2 at several G9a target genes. BIX-01294 (5 µM) reduces levels of global H3K9 methylation in pronuclear- and 2-cell-stage embryos. Embryos transiently exposed to BIX-01294 have a reduced ability to establish pregnancy. BIX-01294 (1 µg/mL) causes reduction in the BrdU incorporation of fetal PASMCs. BIX-01294 treatment decreases the PASMCs migration induced by PDGF. | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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