- BIX 01294; BIX01294,BIX-01294
货号： abs810698
| 货号-规格 | 货期 | 价格 | 数量 |
| abs810698-5mg | 现货 | ￥2022.00 | - + |
| abs810698-50mg | 现货 | ￥4669.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM. | |
| 纯度 | ＞98% | |
| 储存/保存方法 | store at -20℃ for one year（Powder）；
in DMSO or others solvent store at 2-4℃ for two weeks, at -80℃ for six months. | |
| 基本信息 | ||
| 别名 | BIX 01294; BIX01294,BIX-01294 | |
| 外观 | Off-white solid | |
| 可溶性/溶解性 | H2O : 14.29 mg/mL (29.13 mM; Need ultrasonic) | |
| 生物活性 | ||
| 靶点 | G9a | |
| In vitro(体外研究) | BIX-01294 (4.1 μM) treatment of G9anull ES cells results in a further reduction in H3K9me2 levels. BIX-01294 reduces H3K9me2 at several G9a target genes. BIX-01294 (5 µM) reduces levels of global H3K9 methylation in pronuclear- and 2-cell-stage embryos. Embryos transiently exposed to BIX-01294 have a reduced ability to establish pregnancy. BIX-01294 (1 µg/mL) causes reduction in the BrdU incorporation of fetal PASMCs. BIX-01294 treatment decreases the PASMCs migration induced by PDGF. | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
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Certificate of Analysis(COA)
