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  • 1,2-双(庚酰硫基)甘油胆碱磷酸

    • [(2S)-2,3-Bis(Heptanoylsulfanyl)Propyl] 2-(Trimethylazaniumyl)Ethyl Phosphate
    货号: abs42002399
    CAS号: 89019-63-6
    分子式: C22H44NO6PS2
    分子量: 513.7
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    货号-规格 货期 价格 数量
    abs42002399-5mg 6-8周 ¥3740.00
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    产品描述
    描述
    1,2-bis(Heptanoylthio)glycerophosphocholine is a synthetic thiol phosphoglyceride lipid derived from D-mannitol which functions as a substrate for PLA2 (phospholipase A2). Hydrolysis of 1,2-bis(Heptanoylthio)glycerophosphocholine by PLA2 produces free thiols, which may be derivitized with dithionitrobenzoic acid to form the chromophore for a spectrophotometric assay of intracellular and membrane-bound PLA2 activity. Release of Arachidonic Acid from membrane phospholipids mediated by PLA2 is thought to regulate eicosanoid production and marked PLA2 activity is observed in correlation with inflammation states. Inhibitors of PLA2 activity, presenting potential intervention upon the inflammatory role of PLA2, have been identified using this assay design. 1,2-bis(Heptanoylthio)glycerophosphocholine is a substrate of PLA1.
    应用
    A lipid tool for assay of PLA2 activity
    纯度
    98%
    储存/保存方法
    Store at -20° C
    形态
    Liquid
    基本信息
    沸点
    78° C
    荧光
    λex 360 nm, λem 460 nm
    可溶性/溶解性
    Soluble in methanol (5 mg/ml), and Tris buffer pH 8.5 (5 mg/ml).
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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