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  • Biotinylated Human FGFR1 alpha (IIIc) Protein
    • FGFR1 alpha (IIIc) 蛋白;FGF R1a; FGFR1 alpha
    货号: abs04964
    产品说明书
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    货号-规格 货期 价格 数量
    abs04964-100μg 1-2周 ¥5250.00
    - +
    abs04964-500μg 1-2周 ¥17500.00
    - +
    abs04964-1mg 1-2周 ¥35000.00
    - +
    大包装询价
    概述
    别名
    FGFR1 alpha (IIIc) 蛋白;FGF R1a; FGFR1 alpha
    种属
    Human
    来源
    Biotinylated Human FGFR1 alpha (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal.;It contains Arg22-Glu374.
    分子量
    The protein has a predicted MW of 42 KDa. Due to glycosylation, the protein migrates to 68-80 KDa based on Bis-TrisPAGE result.
    形态
    Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.
    性能
    序列
    Arg22-Glu374
    标签
    C-His-Avi
    纯度
    > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
    内毒素水平
    Less than 1 EU per μg by the LAL method.
    储存/保存方法
    The product should be stored at -70℃ or -20℃.
    靶标
    背景说明
    Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
    Accession
    P11362
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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