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  • [Met(O)35]-β-Amyloid (1-42)

    • [Met(O)35]-beta-Amyloid (1 - 42) ;(Met(O)35)-Amyloid β-Protein (1-42)
    货号: abs45152893
    CAS号: 1802086-68-5
    分子式: C203H311N55O61S
    分子量: 4530.1
    产品说明书
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    货号-规格 货期 价格 数量
    abs45152893-1mg 4周 ¥4278.00
    - +
    abs45152893-5mg 4周 ¥7518.00
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    大包装询价
    产品描述
    描述
            β-amyloid 1-42, the major protein component of brain senile plaques in Alzheimer's disease, is known to be directly responsible for the production of free radicals toxic to brain tissue. The redox state of Met-35 seems to play a role in peptide's neurotoxic actions by altering the cell deatch pathway mediated by Bax / Blc2. In this peptide, Met35 is in the sulfoxide form.
            (Met(O)35)-Amyloid β-protein (1-42), in contrast to Aβ 1-42, has been shown to be non-toxic to 9-11 day-old rat embryonic hippocampal neuronal cultures and not to produce any protein oxidation. It has also been demonstrated that fibril formation is not affected by Met(O)35.
    来源
    synthesis
    序列
    H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met(O)-Val-Gly-Gly-Val-Val-Ile-Ala-OH
    纯度
    ≥95%
    储存/保存方法
    -20°C,有效期2年。
    基本信息
    别名
    [Met(O)35]-beta-Amyloid (1 - 42) ;(Met(O)35)-Amyloid β-Protein (1-42)
    外观
    Lyophilized powder
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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