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  • Azelaic acid
    • 壬二酸;Nonanedioic acid
    货号: abs816963
    CAS号: 123-99-9
    分子式: C9H16O4
    分子量: 188.22
    产品说明书
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    货号-规格 货期 价格 数量
    abs816963-50mg 1-2周 ¥309.00
    - +
    abs816963-100mg 1-2周 ¥419.00
    - +
    abs816963-200mg 1-2周 ¥617.00
    - +
    abs816963-500mg 1-2周 ¥1191.00
    - +
    大包装询价
    产品描述
    描述

    Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.

    纯度
    >98%
    储存/保存方法
    store at -20℃ for one year(Powder);
    in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
    基本信息
    别名
    壬二酸;Nonanedioic acid
    外观
    白色粉末
    可溶性/溶解性
    DMSO : 35 mg/mL (186 mM)

    Ethanol : 35 mg/mL (186 mM)

    Water : 34 mg/mL (180.6 mM)
    生物活性
    In vitro(体外研究)
    AZ(Azelaic acid) combined with taurine (Tau) show more inhibitory effects in melanocytes than the treatment of AZ alone. AZ combined with Tau inhibits the melanin production and tyrosinase activity of B16F10 melanoma cells without significant cytotoxicity. Also inhibitory effects after treatment with these combined chemical are stronger than AZ alone on melanogenesis.
    In vivo(体内研究)
    Azelaic acid exhibits an anti-atherogenic effect. Its athero-protective effect is not related to changes in plasma lipid content. Azelaic acid supplementation decreases the level of CD68 macrophage marker by 34% (p.
    参考文献
    参考文献
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