anti-HDAC6 Polyclonal Antibody
- HDAC6抗体;CPBHM,HD6,JM21,PPP1R90
货号： abs134070
| 货号-规格 | 货期 | 价格 | 数量 |
| abs134070-50ul | 1-2周 | ￥1500.00 | - + |
大包装询价| 概述 | |
| 别名 | HDAC6抗体;CPBHM,HD6,JM21,PPP1R90 |
| 宿主 | Rabbit |
| 反应种属 | Human;Mouse;Rat |
| 应用 | WB 1:500 - 1:2000 |
| 分子量 | Detects a band of approximately 170kD (Predicted molecular weight: 114kD/131kD) |
| 免疫原 | Recombinant fusion protein containing a sequence corresponding to amino acids 836-1104 of human HDAC6 (NP_006035.2). |
| 阳性对照 | HepG2,Mouse kidney,Rat kidney |
| 性能 | |
| 纯化方法 | Affinity purification |
| 同种型 | IgG |
| 储存/保存方法 | Store at -20℃. Avoid freeze / thaw cycles. |
| 存储溶液 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 靶标 | |
| 背景说明 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Cell projection,Cytoplasm,Nucleus,Perikaryon,axon,dendrite |
| UniProt | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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- Histone deacetylase 6 inhibition mitigates renal fibrosis by suppressing TGFß and EGFR signaling pathways in obstructive nephropathy
Xingying Chen, Chao Yu, Xiying Hou, Jialu Li, Tingting Li, Andong Qiu, Na Liu, and Shougang Zhuang
American Journal of Physiology-Renal Physiology. 2020 Oct 26 .
影响因子： 3.144
Certificate of Analysis(COA)
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