AL 8697
- AL-8697；AL8697
货号： abs814686
| 货号-规格 | 货期 | 价格 | 数量 |
| abs814686-10mg | 4周 | ￥7084.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | AL8697 is a selective p38 MAPK(mitogen-activated protein Kinase) inhibitor, which is also named P38 α inhibitor. It has the function of inhibiting the activity of P38 MAPK.[ | |
| 纯度 | 98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | AL-8697；AL8697 | |
| 外观 | White solid | |
| 可溶性/溶解性 | Soluble in DMSO > 10 mM | |
| 生物活性 | ||
| 靶点 | p38 | |
| In vitro(体外研究) | AL8697 function by the inhibition of P38 MAPK. It regulates a variety of cell activities related with P38 MAPK. | |
| In vivo(体内研究) | In a rat adjuvant-induced arthritis model, AL8697 exhibited a good anti-inflammatory effect and induced leukocytosis and increased total plasma cholesterol, these properties were evidently at 10 mg/kg. In addition, AL8697 partially restored the platelet count. The complex profile for AL8697 in rat AIA (adjuvant-induced arthritis) is not observed in human RA (rheumatoid arthritis). | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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