5'-Fluoroindirubinoxime
- 5'-FIO
货号： abs819772
| 货号-规格 | 货期 | 价格 | 数量 |
| abs819772-10mg | 4周 | ￥2641.00 | - + |
| abs819772-50mg | 4周 | ￥8254.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | 5’-Fluoroindirubinoxime is an antiproliferative agent and an inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3). This compound has been shown to be selective for FMT3 against 6 other kinases including EGFR. | |
| 纯度 | 98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | 5'-FIO | |
| 可溶性/溶解性 | DMSO : 83.33 mg/mL (282.22 mM; Need ultrasonic) | |
| 生物活性 | ||
| In vitro(体外研究) | 5'-Fluoroindirubinoxime (5’-FIO, compound 13) exhibits IC50 values of 1.53 μM and 1.27 μM for VEGFR2 and Aurora A, respectively. 5'-Fluoroindirubinoxime (5’-FIO) exhibits IC50 values of 12.2 μM, 2.1 μM, 3.4 μM and 5.1 μM in A549, SNU-638, HT-1080 and RK3E-ras cancer cells, respectively. 5'-Fluoroindirubinoxime (5’-FIO) induces the apoptosis in RK3E-ras cells. | |
| In vivo(体内研究) | 5'-Fluoroindirubinoxime (5’-FIO, 10 μmol/L/100 μL (~2.95 mg/mL) every other day beginning on day 6, S.C..) exhibits significant anti-tumor activity in rats. | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
共 0张，还能上传 8张 提交
- 提示： 尊敬的客户您好，如果您对我们的产品有什么疑问或想要了解的，可以点击“我要提问”按钮填写您的疑问。
提交不成功？请联系info@absin.cn。
Certificate of Analysis(COA)
