11α-hydroxy Testosterone
货号: abs47045697
货号-规格 | 货期 | 价格 | 数量 |
abs47045697-1mg | 4周 | ¥1132.00 | - + |

产品描述 | ||
描述 | 11α-hydroxy Testosterone is a metabolite of testosterone, produced by the cytochrome P450 (CYP) isoform CYP3A.1 It can also be generated from testosterone by a mutant of CYP107A1 and from 11α-hydroxy progesterone by the fungus B. bassiana.2,3 The biological activity of this metabolite has not been elucidated. | |
纯度 | ≥97% | |
储存/保存方法 | Store at 4℃ | |
参考文献 | ||
参考文献 | 1.Zhao, Q. and Li, Z. Synthesis of 11-substituted androstenediones and testosterones as human decidual cell growth inhibitors. Steroids 59, 190-195 (1994). 2.Xiang, H.,Tschirret-Guth, R.A. and Ortiz de Montellano, P.R. An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates. The Journal of Biological Chemisty 275(46), 35999-36006 (2000). 3.Swizdor, A.,Kolek, T.,Panek, A., et al. Microbial Baeyer-Villiger oxidation of steroidal ketones using Beauveria bassiana: Presence of an 11α-hydroxyl group essential to generation of D-homo lactones. Biochim.Biophys.Acta. 1811(4), 253-262 (2011). | |
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