11β-Prostaglandin E2

11β-PGE2 is the C-11 epimer of PGE2 and is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a K_i = 53 nM. 11β-PGE2 has been shown to stimulate bone resorption in rats and to inhibit PGE2 binding to the prostaglandin transporter protein K_i = 56 nM. These prostaglandin analogues are integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.

An epimer of PGE2 shown to moderately inhibit PGE2 binding to rat hypothalamic membranes

0.5 wt. % in methyl acetate

Store at -20° C

11-EpiprostaglandinE2; 11-epi-PGE2; 11-epi-Prostaglandin E2; 11b-PGE2

A solution in methyl acetate