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  • (±)11-HDoHE
  • 11-hydroxy Docosahexaenoic Acid
  • 货号: abs42000304
    CAS号: 87018-59-5
    分子式: C22H32O3
    分子量: 344.5
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    货号-规格 货期 价格 数量
    abs42000304-25ug 4周 ¥1200.00
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    abs42000304-50ug 4周 ¥2002.00
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    大包装询价
    产品描述
    描述

    (±)11-HDoHE is an autoxidation product of docosahexaenoic acid (DHA) in vitro (1,2) and also produced from incubations of DHA in rat brain, intestinal microsomes and liver.3,4,5 DHA is metabolized to 11(S)-HDoHE by human platelets and canine retina.6,7,8,5 In addition to 11(S)-HDoHE, 14(S)-HDoHE is also produced by platelets. 11(S)-HDoHE was shown to be an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 50, 4.7, and 7.5μM, respectively. It is a potential marker of oxidative stress in brain and retina where DHA is abundant.

    应用
    A potential marker of oxidative stress
    纯度
    ≥98%
    储存/保存方法
    Store at -20° C
    形态
    Liquid
    基本信息
    别名
    11-hydroxy Docosahexaenoic Acid
    外观
    solution in ethanol
    沸点
    78° C
    折射率
    n20D 1.53 (Predicted)
    可溶性/溶解性
    Soluble in DMSO, DMF, and PBS (pH 7.2) (~0.8 mg/ml).
    MDL
    MFCD02262229
    PubChem CID
    11631564
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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