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  • (±)11(12)-EET
  • (±)11,12-EpETrE;
  • 货号: abs47044860
    CAS号: 123931-40-8
    分子式: C20H32O3
    分子量: 320.5
    产品说明书
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    货号-规格 货期 价格 数量
    abs47044860-100ug 4周 ¥3542.00
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    产品描述
    描述
    (±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.1,2 ​(±)11(12)-EET has been shown, along with (±)8(9)-EET (Item No. 50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells.3
    纯度
    ≥95%
    储存/保存方法
    Store at -20℃
    基本信息
    别名
    (±)11,12-EpETrE;
    参考文献
    参考文献
    1.Chacos, N.,Falck, J.R.,Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochemical and Biophysical Research Communications 104, 916-922 (1982).

    2.Oliw, E.H.,Guengerich, F.P. and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. The Journal of Biological Chemisty 257, 3771-3781 (1982).

    3.Graber, M.N.,Alfonso, A. and Gill, D.L. Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid. The Journal of Biological Chemisty 272, 29546-29553 (1997).

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