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  • (5Z,13E,15R)-15-羟基-16,16-二甲基-9-氧代-前列腺-5,13-二烯-1-酸

    • (5Z,13E,15R)-15-Hydroxy-16,16-Dimethyl-9-Oxo-Prosta-5,13-Dien-1-Oic Acid,11-Deoxy-16,16-dimethyl-PGE2;15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,13-dienoic acid; AY 24609
    货号: abs42003365
    CAS号: 53658-98-3
    分子式: C22H36O4
    分子量: 364.5
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    产品描述
    描述
    11-deoxy-16,16-dimethyl Prostaglandin E2 is a stable synthetic analog of PGE2 , that has been shown to act as a selective agonist for both EP2 and EP3 receptors, unlike PGE2 which agonizes a variety of prostanoid receptors. This compound has shown effective inhibition of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively, and is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.
    应用
    An analog of PGE2 shown to act as a selective agonist for EP2 & EP3 receptors
    纯度
    >98%
    储存/保存方法
    Store at -20° C
    形态
    Liquid
    基本信息
    别名
    11-Deoxy-16,16-dimethyl-PGE2;15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,13-dienoic acid; AY 24609
    沸点
    57° C
    折射率
    n20D 1.54 (Predicted)
    可溶性/溶解性
    Soluble in water (>5 mg/ml at 25° C), PBS (pH 7.2) (~5 mg/ml), ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml).
    MDL
    MFCD00135216
    PubChem CID
    3246818
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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