(5Z,13E,15R)-15-羟基-16,16-二甲基-9-氧代-前列腺-5,13-二烯-1-酸
- (5Z,13E,15R)-15-Hydroxy-16,16-Dimethyl-9-Oxo-Prosta-5,13-Dien-1-Oic Acid,11-Deoxy-16,16-dimethyl-PGE2;15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,13-dienoic acid; AY 24609
货号: abs42003365
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产品描述 | |
描述 | 11-deoxy-16,16-dimethyl Prostaglandin E2 is a stable synthetic analog of PGE2 , that has been shown to act as a selective agonist for both EP2 and EP3 receptors, unlike PGE2 which agonizes a variety of prostanoid receptors. This compound has shown effective inhibition of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively, and is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro. |
应用 | An analog of PGE2 shown to act as a selective agonist for EP2 & EP3 receptors |
纯度 | >98% |
储存/保存方法 | Store at -20° C |
形态 | Liquid |
基本信息 | |
别名 | 11-Deoxy-16,16-dimethyl-PGE2;15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,13-dienoic acid; AY 24609 |
沸点 | 57° C |
折射率 | n20D 1.54 (Predicted) |
可溶性/溶解性 | Soluble in water (>5 mg/ml at 25° C), PBS (pH 7.2) (~5 mg/ml), ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml). |
MDL | MFCD00135216 |
PubChem CID | 3246818 |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
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