首页 产品中心
  • 1-Oleoyl lysophosphatidic acid sodium salt
  • Lysophosphatidic acid;LPA
  • 货号: abs819548
    CAS号: 325465-93-8
    分子式: C21H40O7P.Na
    分子量: 458.5
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs819548-5mg 4周 ¥1134.00
    - +
    abs819548-10mg 4周 ¥2090.00
    - +
    大包装询价
    产品描述
    描述

    1-Oleoyl lysophosphatidic acid (LPA) is a naturally occurring phospholipid with various effects. LPA is widely distributed in many tissues. Similar to many other biomediators, LPA interacts with cells via specific cell surface receptors, such as G proteincoupled receptors, to induce biological effects.

    纯度
    98%
    储存/保存方法
    Store at -20°C
    基本信息
    别名
    Lysophosphatidic acid;LPA
    外观
    Off-White Solid
    可溶性/溶解性
    PBS
    生物活性
    In vitro(体外研究)
    LPA could mediate signal transduction via Edg/LPA receptor, inducing the proliferation, migration, adhesion and antiapoptotic function of tumor cells. Additionally, LPA was found to elicit upregulation of VEGF, leading to an indirect influence on initiation and progression of malignancies. LPA could also stimulate matrix metalloproteinase secretion and tumor angiogenesis factor .
    In vivo(体内研究)
    LPA was tested for its vascular remodeling effect in a rat model of hypoxic pulmonary hypertension. Serum from animals in the hypoxic group showed higher chemoattractant properties toward rat primary lung fibroblasts, and such cell migration increase was prevented by the LPA receptor 1 and 3 antagonists. LPA also found to increase adhesive properties of human pulmonary artery endothelial cells, via the activation of LPA receptor 1 or 3.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
        提示: 尊敬的客户您好,如果您对我们的产品有什么疑问或想要了解的,可以点击“我要提问”按钮填写您的疑问。
        提交不成功?请联系info@absin.cn。
        我要提问

    促销资讯 更多

      订购信息
      您可以从我们的授权经销商处购买absin产品或获得技术支持。若要查看您所在地区的经销商,请从以下的下拉列表中选择。
      GO
      • 0