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  • Rabbit anti-14-3-3 beta Polyclonal Antibody
  • 14 3 3 alpha; 14 3 3 protein beta/alpha; 14-3-3 protein beta/alpha; 1433B_HUMAN; Brain protein 14 3 3 beta isoform; GW128; HS 1; KCIP-1; KCIP1; N-terminally processed; Protein 1054; Protein kinase C inhibitor protein 1; YWHAA; YWHAB;
  • 货号: abs133792
    产品说明书
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    货号-规格 货期 价格 数量
    abs133792-50ug 1-2周 ¥1100.00
    - +
    abs133792-100ug 1-2周 ¥1650.00
    - +
    大包装询价
    概述
    别名
    14 3 3 alpha; 14 3 3 protein beta/alpha; 14-3-3 protein beta/alpha; 1433B_HUMAN; Brain protein 14 3 3 beta isoform; GW128; HS 1; KCIP-1; KCIP1; N-terminally processed; Protein 1054; Protein kinase C inhibitor protein 1; YWHAA; YWHAB;
    宿主
    Rabbit
    特异性
    14-3-3 β Antibody detects endogenous levels of total 14-3-3 β.
    反应种属
    Human;Mouse;Rat
    预测反应种属
    Chicken;Rabbit;Sheep;Dog;Bovine;Horse;
    应用
    WB 1:500~1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    免疫原
    A synthesized peptide.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
    靶标
    背景说明
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
    翻译后修饰
    The alpha, brain-specific form differs from the beta form in being phosphorylated. Phosphorylated on Ser-60 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion.
    细胞定位
    Cytosol;Extracellular region or secreted;Mitochondrion;Nucleus;
    UniPort
    Western blot analysis of extracts from HepG2 cells and Jurkat cells, using 14-3-3 β antibody.
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