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Rabbit anti-CIRBP Polyclonal Antibody

A18 hnRNP; A18HNRNP; cirbp; CIRBP_HUMAN; CIRP; Cold inducible RNA binding protein; Cold-inducible RNA-binding protein; Glycine rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39;

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货号 abs133022
规格 价格
¥950
库存状态:1-2周
¥1450
库存状态:1-2周

数量:

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概述
描述 Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
别名 A18 hnRNP; A18HNRNP; cirbp; CIRBP_HUMAN; CIRP; Cold inducible RNA binding protein; Cold-inducible RNA-binding protein; Glycine rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39;
来源宿主 Rabbit
特异性 CIRBP antibody detects endogenous levels of total CIRBP.
应用 WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
反应种属
Human, Mouse, Rat
预测反应种属 Xenopus
免疫原 A synthesized peptide.
性能
浓度 1mg/ml
保存方法 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
存储溶液 Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
类型 Polyclonal
UniProt Q14011
纯化方法 The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
分子量 18 kDa
实验结果图
Western blot analysis of CIRBP expression in  HCT116 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of CIRBP expression in HCT116 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide.