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Recombinant Mouse Interleukin-16/IL-16

Pro-interleukin-16,Interleukin-16,Lymphocyte chemoattractant factor,LCF, REF: C1011

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货号 abs04469
规格 价格
¥ 840
库存状态:1-2周
¥ 2520
库存状态:1-2周
¥ 12320
库存状态:1-2周
¥ 17600
库存状态:1-2周

数量:

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概述
描述 Recombinant Mouse Interleukin-16 is produced by our E.coli expression system and the target gene encoding Ser1205-Ser1322 is expressed with a 6His tag at the N-terminus.
别名 Pro-interleukin-16,Interleukin-16,Lymphocyte chemoattractant factor,LCF, REF: C1011
形态 Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH 8.0.
来源 E.coli
氨基酸序列 MGSSHHHHHHSSGLVPRGSHMSAASASAASDISVESKEATVCTVTLEKTSAGLGFSLEGGKGSLH GDKPLTINRIFKGTEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQC KQTTASADS
内毒素水平 Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession # O54824
背景 Mouse interleukin-16(IL-16) is a single chain non-glycosylated polypeptide. IL-16 is widely expressed in human tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. IL-16 plays an important role instimulating a migratory response in CD4+ lymphocytes, monocytes, and eosinophils,inducing T-lymphocyte expression of interleukin 2 receptor.It was originally identified as a CD8+ T cell-derived chemoattractant for CD4+ cells. In addition to its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro and appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. It may act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
性能
纯度 Greater than 95% as determined by reducing SDS-PAGE.